Pituitary cretinism in two sisters.
- 1 September 1980
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 55 (9), 725-727
- https://doi.org/10.1136/adc.55.9.725
Abstract
Two sisters with cretinism are reported. Each showed low levels of serum triiodothyronine, thyroxine, and thyroid-stimulating hormone (TSH). In the elder sister, serum TSH did not increase after administration of thyrotropin-releasing hormone. We conclude that cretinism in these 2 sisters was due to TSH deficiency. This is the second report of 'familial' pituitary cretinism (TSH-deficient congenital hypothyroidism).This publication has 11 references indexed in Scilit:
- ISOLATED THYROTROPHIN DEFICIENCY IN DIABETES MELLITUSActa Endocrinologica, 1977
- Isolated Thyrotropin Deficiency With Thyrotropin-Releasing- Hormone Induced TSH Secretion and Thyroidal ReleaseJournal of Clinical Endocrinology & Metabolism, 1976
- Congenital hypothyroidism in a young man with growth hormone, thyrotropin, and prolactin deficienciesThe Journal of Pediatrics, 1976
- [Isolated thyrotropin deficiency--a case with abnormal leukocyte function].1975
- Idiopathic Sexual Precocity in a Boy with Growth Hormone, Prolactin and Thyrotropin DeficienciesJournal of Clinical Endocrinology & Metabolism, 1974
- Prolactin Stimulation by Thyrotropin-Releasing Hormone in a Patient with Isolated Thyrotropin DeficiencyNew England Journal of Medicine, 1972
- Familial Isolated Thyrotropin Deficiency with CretinismNew England Journal of Medicine, 1971
- Studies in pseudohypoparathyroidismThe American Journal of Medicine, 1969
- Pseudohypoparathyroidism and selective deficiency of thyrotropin: An interesting associationMetabolism, 1967
- Isolated Lack of Thyrotropin in ManJournal of Clinical Endocrinology & Metabolism, 1966