Breaking the 1000-gene barrier for Mimivirus using ultra-deep genome and transcriptome sequencing
Open Access
- 4 March 2011
- journal article
- research article
- Published by Springer Nature in Virology Journal
- Vol. 8 (1), 99
- https://doi.org/10.1186/1743-422x-8-99
Abstract
Mimivirus, a giant dsDNA virus infecting Acanthamoeba, is the prototype of the mimiviridae family, the latest addition to the family of the nucleocytoplasmic large DNA viruses (NCLDVs). Its 1.2 Mb-genome was initially predicted to encode 917 genes. A subsequent RNA-Seq analysis precisely mapped many transcript boundaries and identified 75 new genes.Keywords
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