GADOLINIUM-DTPA ENHANCEMENT OF EXPERIMENTAL SOFT-TISSUE CARCINOMA AND HEMORRHAGE IN MAGNETIC-RESONANCE-IMAGING

  • 1 January 1987
    • journal article
    • research article
    • Vol. 28 (1), 75-78
Abstract
An experimental series in the rabbit was performed to test gadolinium-DTPA (Gd-DTPA) enhancement of VX-2 carcinoma and hemorrhages induced in the soft tissues. The recognition of both malignant and benign lesions was greatly facilitated on T1 weighted images after intravenous adminstration of 0.3 mmol Gd-DTPA/kg body weight because of reduced T1 relaxation times, Gd-DTPA enhancement reached its maximum after 10-15 minutes and was most apparent in tumor tissue, connective tissue surrounding the tumor and in the area of fresh hemorrhage.