Ventricular distensibility and pressure-volume curve during sympathetic stimulation

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Abstract
Experiments with an isovolumically contracting canine left ventricle preparation do not indicate that sympathetic cardiac nerve stimulation induces any alteration in ventricular distensibility. If the heart rate is sufficiently high to produce incomplete ventricular relaxation, sympathetic stimulation, by shortening systole, restores the relaxed pressure-volume relation without any indication, however, that ventricular distensibility is changed.