THE ELIMINATION OF ADMINISTERED COBALT IN PANCREATIC JUICE AND BILE OF THE DOG, AS MEASURED WITH ITS RADIOACTIVE ISOTOPES

Abstract

Pancreatic juice and bile were compared as vehicles for the elimination of intravenously injected Co. The use of radioactive isotopes of this element permitted the introduction of as little as 10 to 26 [gamma] in dogs weighing 16-19 kg. The dogs were provided with either a single bile or pancreatic fistula or with both pancreatic and bile fistulae. Significant amts. of Co were not eliminated in pancreatic juice. Appreciable amts. did appear in the bile; a total of 5% of the intravenously injected Co was contained in the bile collected during a period of approx. 72 hrs.