Geometric packing constraints in egg phosphatidylcholine vesicles.
- 1 January 1978
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 75 (1), 308-310
- https://doi.org/10.1073/pnas.75.1.308
Abstract
This investigation presents a quantitative analysis of the asymmetric transmembrane lipid packing geometry in egg phosphatidylcholine vesicles. The analysis uses hydrodynamic and nuclear magnetic resonance data obtained for homogeneous egg phosphatidylcholine vesicles and demonstrates that the average area per lipid head group and effective length of the lipid are greater on the outer monolayer than on the inner monolayer of the egg phosphatidylcholine vesicle. Results also indicate that the bilayer of the egg phosphatidylcholine vesicles has an asymmetrical interface through its center.This publication has 16 references indexed in Scilit:
- Phospholipid head-group conformations; intermolecular interactions and cholesterol effectsBiochemistry, 1977
- Theory of lipid monolayer and bilayer phase transitions: Effect of headgroup interactionsThe Journal of Membrane Biology, 1976
- Direct spectroscopic observation of inner and outer hydrocarbon chains of lipid bilayer vesicles.Proceedings of the National Academy of Sciences, 1976
- Structure in the polar head region of phospholipid bilayers: a phosphorus-31 {proton} nuclear Overhauser effect studyBiochemistry, 1976
- Headgroup conformation and lipid--cholesterol association in phosphatidylcholine vesicles: a 31P(1H) nuclear Overhauser effect study.Proceedings of the National Academy of Sciences, 1975
- Differential Interaction of Cholesterol with Phosphatidylcholine on the Inner and Outer Surfaces of Lipid Bilayer VesiclesProceedings of the National Academy of Sciences, 1974
- Lipid Bilayer Phase Transition: Density Measurements and TheoryProceedings of the National Academy of Sciences, 1973
- Diffusion studies on phosphatidylcholine vesiclesJournal of the American Chemical Society, 1973
- Effect of sonication on the structure of lecithin bilayersBiochemistry, 1972
- Structure des phases liquide-cristallines de différents phospholipides, monoglycérides, sphingolipides, anhydres ou en présence d'eauJournal of Molecular Biology, 1967