Post-herpetic neuralgia and topical capsaicin
- 1 June 1988
- journal article
- research article
- Published by Wolters Kluwer Health in Pain
- Vol. 33 (3), 333-340
- https://doi.org/10.1016/0304-3959(88)90292-8
Abstract
In relief after 4 weeks. Seventy-eight percent of the 23 noted at least some improvement in pain. Post-capsaicin burning was a common, untoward effect in most patients and in about one-third was so unbearable that the trial was terminated prematurely. This treatment appears to be a useful modality in PHN, particularly in the elderly in whom oral medications are often poorly tolerated; however, it does require supervision. A double-blind, controlled trial is now necessary. ∗Correspondence to: C. Peter N. Watson, Smythe Pain Clinic, Toronto General Hospital, Toronto, Ont. M5G 2C4, Canada. (Received 17 November 1987; revised 13 January 1988; accepted 24 January 1988.) © Lippincott-Raven Publishers....Keywords
This publication has 11 references indexed in Scilit:
- Treatment of chronic postherpetic neuralgia with topical capsaicin: A preliminary studyJournal of the American Academy of Dermatology, 1987
- Treatment of Postherpetic NeuralgiaClinical Neuropharmacology, 1986
- Amitriptyline versus placebo in postherpetic neuralgiaNeurology, 1982
- Intrathecal Capsaicin Depletes Substance P in the Rat Spinal Cord and Produces Prolonged Thermal AnalgesiaScience, 1979
- Capsaicin-induced depletion of substance P from primary sensory neuronesBrain Research, 1978
- Pharmacologically induced selective degeneration of chemosensitive primary sensory neuronesNature, 1977
- Release of substance P-like immunoreactivity from isolated spinal cord of newborn ratNature, 1976
- DIRECT EVIDENCE FOR NEUROGENIC INFLAMMATION AND ITS PREVENTION BY DENERVATION AND BY PRETREATMENT WITH CAPSAICINBritish Journal of Pharmacology and Chemotherapy, 1967
- THE NATURAL HISTORY OF HERPES ZOSTERJAMA, 1957
- The Outcome of Patients with Herpes ZosterArchives of Dermatology, 1957