2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF
Top Cited Papers
Open Access
- 1 April 2003
- journal article
- research article
- Published by Elsevier in Cancer Cell
- Vol. 3 (4), 363-375
- https://doi.org/10.1016/s1535-6108(03)00077-1
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- 2-Methoxyestradiol overcomes drug resistance in multiple myeloma cellsBlood, 2002
- Hypoxia — a key regulatory factor in tumour growthNature Reviews Cancer, 2002
- Generation of bidirectional hypoxia/HIF-responsive expression vectors to target gene expression to hypoxic cellsGene Therapy, 2001
- Hypoxia: the tumor's gateway to progression along the angiogenic pathwayTrends in Cell Biology, 2001
- Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylationThe EMBO Journal, 2001
- SOD1 Down-Regulates NF-κB and c-Myc Expression in Mice after Transient Focal Cerebral IschemiaJournal of Cerebral Blood Flow & Metabolism, 2001
- Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based ScreenScience, 1999
- Inhibition of Tumor Necrosis Factor α-Stimulated Aromatase Activity by Microtubule-Stabilizing Agents, Paclitaxel and 2-MethoxyestradiolBiochemical and Biophysical Research Communications, 1999
- Abnormal blood vessel development and lethality in embryos lacking a single VEGF alleleNature, 1996
- The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growthNature, 1994