The major internal protein, p27, of a retrovirus-like particle participates in immune complex formation in psoriasis
- 1 March 1985
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 86 (1-2), 37-45
- https://doi.org/10.1007/bf01314112
Abstract
The major internal protein, p27, of a retrovirus-like particle isolated from the urine of a patient with psoriasis has been purified and used in an indirect ELISA to detect human antibodies against the virus antigen. Rabbit anti-p27 antiserum has been applied to detect p27 antigen present in clinical specimens. p27 and anti-p27 antibodies have been demonstrated in extracts from psoriatic scales. Insignificant amounts of free anti-p27 antibodies are present in serum, but both p27 and anti-p27 antibodies have been detected in circulating immune complexes obtained from serum or synovial fluid from patients with psoriatic arthritis.This publication has 30 references indexed in Scilit:
- The major internal protein, p27, of a retrovirus-like particle is expressed in blood lymphocytes from psoriatic patientsArchiv für die gesamte Virusforschung, 1985
- Preparative Isolation of Immune Complexes from Serum by Sucrose Gradient UltracentrifugationScandinavian Journal of Immunology, 1984
- URINE PROTEINS CROSS‐REACTING WITH ANTISERUM AGAINST VIRUS‐LIKE PARTICLES FROM CULTURED PSORIATIC EPITHELIAL CELLSActa Pathologica Microbiologica Scandinavica Series B: Microbiology, 1983
- A VIRUS‐LIKE PARTICLE ASSOCIATED WITH PSORIASISActa Pathologica Microbiologica Scandinavica Series B: Microbiology, 1983
- CHARACTERIZATION OF VIRUS‐LIKE PARTICLES FROM A PSORIATIC PATIENT WITH RESPECT TO THE POSSIBLE PRESENCE OF PARTICLE‐ASSOCIATED RNA AND RNA‐DIRECTED DNA POLYMERASEActa Pathologica Microbiologica Scandinavica Series B: Microbiology, 1983
- ISOLATION OF VIRUS‐LIKE PARTICLES IN URINE FROM A PSORIATIC PATIENTActa Pathologica Microbiologica Scandinavica Series B: Microbiology, 1983
- Circulating immune complexes in the seronegative spondyloarthropathiesClinical Immunology and Immunopathology, 1982
- Evaluation of lymphocyte subpopulations and T-cell functions in psoriasisClinical Immunology and Immunopathology, 1978
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976
- Autoradiographic Analysis of Turnover Times of Normal and Psoriatic Epidermis**From the Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Public Health Service, U.S. Department of Health, Education and Welfare.Journal of Investigative Dermatology, 1965