Estrogenic Activity of the Insecticide Kepone on the Chicken Oviduct
- 28 July 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 201 (4353), 356-358
- https://doi.org/10.1126/science.78523
Abstract
Kepone induces ovalbumin and conalbumin synthesis in explants of chick oviduct in vitro by acting as a weak estrogen. It binds to the nuclear estrogen receptor and is antagonized by the antiestrogen tamoxifen. Kepone also induces egg white protein synthesis in vivo by direct interaction with estrogen receptors and by indirectly increasing the concentration of progesterone in the serum.This publication has 17 references indexed in Scilit:
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