Significance and Nature of Inclusion-Bearing Cells in the Urine of Patients with Measles

Abstract

IT has been shown that during the course of certain acute viral illnesses, cells containing discrete cytoplasmic inclusions appear in the urine.¹ During the pre-eruptive and early-rash stages of measles, these cells are particularly numerous, and their inclusions are quite large. Because of this fact, measles infection seemed to provide the best situation in which to learn more about the nature and significance of the urinary inclusion bodies. The essential purpose of this investigation is aimed at determining if the presence of the inclusion-bearing cells in the urine reflects cytopathic effects of virus in the urine or urinary tract.Materials . . .