Osmotic Fragility of Human Blood Platelets

Abstract

The osmotic fragility of 50 samples of platelets from normal healthy donors has been studied. It has been found that fragility of platelets starts at a concentration of about 0.44 per cent NaCl and is complete at a concentration of 0.34 per cent. The serotonine released from the platelets increased with the gradual disintegration as the saline concentration fell.