Prostaglandin 15 (R) 15-methyl-E2 Methyl Ester for Suppression of Gastric Acidity in Gravida at Term

Abstract
During the second hour after giving 100 μg of orally administered prostaglandin 15 (R) 15-methyl-E2 methyl ester in the pregnant patient at term a noticeable reduction in basal gastric acid secretion took place. At this dose no excessive uterine stimulation was observed. Prostaglandin 15 (R) 15-methyl-E2 methyl ester could prove of value in the preoperative preparation of the pregnant patient before anaesthesia for reducing the incidence of acid regurgitation.