Concepts of multiple congenital contractures (arthrogryposis) in man and animals
- 1 April 1982
- journal article
- research article
- Published by Wiley in Teratology
- Vol. 25 (2), 247-258
- https://doi.org/10.1002/tera.1420250214
Abstract
This is a concept of multiple congenital contractures, based upon clinical experience with the malformation and available literature, leading to a conception of the multiple categories of etiology, which cause neuropathic or myopathic muscle weakness or limb immobilization. The muscle weakness and imbalance of muscle power around the joints elicits a physiological compensatory collagenic response, which replaces atrophied muscle fibers with connective tissue and thickens the joint capsule sufficienty to result in prenatal fixation of limb segments at the joint.Keywords
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