OCCURRENCE AND DETERMINATION OF CONJUGATED SULFATES OF ESTROGENS IN URINE FROM PREGNANT WOMEN
- 1 July 1949
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 45 (1), 86-90
- https://doi.org/10.1210/endo-45-1-86
Abstract
Among 7 samples of urine of late pregnancy, from 5% to 89% of the estriol fraction and from 8% to 100% of the estrone-estradiol fraction were found to be conjugated as the sulfate. This was demonstrated by the use of an enzyme prepn. containing phenol-sulfatase, Evidently the sulfate ester linkage is with the phenolic hydroxyl group at position 3 since phenolsulfatase does not hydrolyze alcoholic sulfates.Keywords
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