Interrelationship Between Substrates and Inhibitors of Human CYP3A and P-Glycoprotein
- 1 January 1999
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 16 (3), 408-414
- https://doi.org/10.1023/a:1018877803319
Abstract
Purpose. CYP3A and P-gp both function to reduce the intracellular concentration of drug substrates, one by metabolism and the other by transmembrane efflux. Moreover, it has been serendipitously...Keywords
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