Reduction of glutathione coupled with oxidative decarboxylation of malate in cattle lens
- 1 February 1953
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 53 (3), 436-444
- https://doi.org/10.1042/bj0530436
Abstract
Reduction of glutathione was coupled through TPN with oxidative decarboxylation of malate in extracts of cattle lens, and the distr. and properties of the 2 enzymes involved (malic enzyme and glutathione reductase) were studied. The malic enzyme was shown to be of the same type as the one in liver described by Ochoa et al. (Jour. Biol. Chem. 174: 979. 1948), and the glutathione reductase was similar to that found by Rail and Lehninger (Jour. Biol. Clin. 194: 119. 1952) in a number of different tissues. The possible function of the coupled reaction in lens metabolism is discussed.Keywords
This publication has 13 references indexed in Scilit:
- GLUTATHIONE REDUCTASE OF ANIMAL TISSUESJournal of Biological Chemistry, 1952
- Studies involving enzymic phosphorylation. 1. The hexokinase activity of rat tissuesBiochemical Journal, 1952
- GLUTATHIONE REDUCTASE OF WHEAT GERMJournal of Biological Chemistry, 1951
- Studies on the crystalline lens: technic for in vitro culture of crystalline lenses and observations.1950
- BIOSYNTHESIS OF DICARBOXYLIC ACIDS BY CARBON DIOXIDE FIXATION .1. ISOLATION AND PROPERTIES OF AN ENZYME FROM PIGEON LIVER CATALYZING THE REVERSIBLE OXIDATIVE DECARBOXYLATION OF L-MALIC ACID1948
- Metabolism of acetoacetate in animal tissues. 11945
- Micro-determination of isocitric and cis-aconitic acids in biological materialBiochemical Journal, 1944
- Alcohol dehydrogenase of animal tissuesBiochemical Journal, 1938
- CHEMISTRY OF THE LENSArchives of Ophthalmology (1950), 1933
- The cuprous derivatives of some sulphydryl compoundsBiochemical Journal, 1931