Secretion of inducible proteinase by pathogenicCandidaspecies
- 1 January 1984
- journal article
- Published by Oxford University Press (OUP) in Medical Mycology
- Vol. 22 (1), 79-82
- https://doi.org/10.1080/00362178485380121
Abstract
The ability of three isolates each of seven pathogenic Candida species to grow in a liquid medium containing bovine serum albumin (BSA) as a nitrogen source was determined. All three strains of C. albicans , two strains of C. guilliermondii and one strain of C. tropicalis grew well. At any time proteinase activity was detected in the culture filtrates of only the most virulent species— C. albicans, C. tropicalis and C. parapsilosis and this observation was related to complete hydrolysis of BSA. Serologically, cross reactions were demonstrated between anti-proteinase antiserum and C. albicans and C. tropicalis culture filtrates. These results further emphasise the role of the inducible proteinase of Candida in the pathogenesis of candidosis.Keywords
This publication has 11 references indexed in Scilit:
- Modification and extension of tests for differentiation ofCandidaspecies and strainsMedical Mycology, 1983
- Antigenic variability betweenCandida albicansblastospores isolated from healthy subjects and patients withCandidainfectionMedical Mycology, 1982
- Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivityAnalytical Biochemistry, 1981
- Laboratory evaluation of antifungal agents: a comparative study of five imidazole derivatives of clinical importanceJournal of Antimicrobial Chemotherapy, 1980
- INDUCIBLE PROTEINASE OF CANDIDA ALBICANS IN DIAGNOSTIC SEROLOGY AND IN THE PATHOGENESIS OF SYSTEMIC CANDIDOSISJournal of Medical Microbiology, 1980
- Purified Candida albicans proteinase in the serological diagnosis of systemic candidosisJAMA, 1980
- Variation de la structure antigenique parietale deCandida albicansmise en evidence au niveau des blastospores d'un antigene P dependant de leur origineMedical Mycology, 1980
- Detection of Candida precipitins. A comparison of double diffusion and counter immunoelectrophoresisJournal of Immunological Methods, 1975
- Proteolytic activity ofCandida spp.as related to the pathogenesis of denture stomatitisMedical Mycology, 1974
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970