A Semiempirical Model for Electroultrafiltration-Diafiltration

Abstract
An exponential relationship between protein concentration and time is used to predict the solution flux when concentrating bovine serum albumin solutions with electroultrafiltration. The time constant can also be predicted from a plot of flux versus the logarithm of the bulk concentration. The limitations of this prediction are also discussed. The average flux during electrodiafiltration is used to predict the exponential relationship between salt concentration and time when using electrodiafiltration to remove NaCl from bovine serum albumin solutions. The processing time saved by using an electric field is easily calculated from these equations.