Localization of four polypeptide hormones in the saurian pancreas

Abstract

Glucagon, insulin, somatostatin, and pancreatic polypeptide have been localized in the anolian pancreas using peroxidase‐antiperoxidase immunocytochemistry. The most abundant endocrine cell type contains glucagon. Insulin‐containing cells are the next most numerous. Somatostatin‐immunoreactive cells tend to be localized at the periphery of the islet cords. Pancreatic polypeptide‐containing cells are a minor endocrine component scattered throughout the exocrine pancreas and occasionally within the islet areas. No staining was observed after application of antigastrin serum.