Erythroid Colony Forming Cells in Aplastic Anaemia
- 1 December 1977
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 37 (4), 483-488
- https://doi.org/10.1111/j.1365-2141.1977.tb01021.x
Abstract
The concentration and erythropoietin dependence of erythropoietic progenitor cells (CFU-E) were examined in 13 patients with aplastic anemia at different stages of their disease. The CFU-E incidence was quantitatively diminished in aplastic anemia but tended to recover to normal values if the disease recovered. The CFU-E showed a qualitatively different response to stimulatinon by erythropoietin, being resistant to low concentrations but responsive to concentrations greater than 0.2 U[units]/ml, whereas there was a linear response in the controls up to 0.5 U/ml.This publication has 15 references indexed in Scilit:
- Granulocytic Progenitor Cells in Aplastic AnaemiaBritish Journal of Haematology, 1977
- Erythropoietin sensitivity as a differentiation marker in the hemopoietic system: Studies of three erythropoietic colony responses in cultureJournal of Cellular Physiology, 1976
- Pathophysiology of Aplastic AnaemiaBritish Journal of Haematology, 1975
- BONE-MARROW CELLS RESISTANT TO CHLORAMPHENICOL IN CHLORAMPHENICOL-INDUCED APLASTIC ANÆMIAThe Lancet, 1975
- The Effect of Erythropoietin on Colonial Growth of Erythroid Precursor Cells In VitroProceedings of the National Academy of Sciences, 1974
- Erythroid colony formation in cultures of mouse and human bone marrow: Analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose‐concanavalin AJournal of Cellular Physiology, 1974
- Granulopoiesis in Neutropenic DisordersBlood, 1973
- Induction of Colonies of Hemoglobin-Synthesizing Cells by Erythropoietin In VitroProceedings of the National Academy of Sciences, 1971
- In Vitro Granulocytic Colony-Forming Potential of Bone Marrow from Patients with Granulocytopenia and Aplastic AnemiaExperimental Biology and Medicine, 1971
- Human bone marrow colony growth in agar‐gelJournal of Cellular Physiology, 1970