Pathogenesis of Experimental Hypertension Produced by Carotid Sinus Area Constriction in Dogs

Abstract

Bilateral constriction of the carotid sinus area, the immediate arterial branches of the sinus, or (perhaps) the vertebral arteries, and bilateral resection of the carotid sinus produces a significant, persistent hypertension in dogs, the highest levels occurring in the carotid sinus area constricted dogs. Pathogenesis is still unsettled.