SOME OBSERVATIONS ON THE METABOLISM OF D-GALACTOSE IN NORMAL MAN

Abstract
Various quantities of galactose-1-C14, when given intravenously to normal human subjects, are rapidly and extensively metabolized to C14O2. This metabolism is markedly slowed by ingestion of ethanol but is not affected by administration of progesterone menthol or pyruvate. White blood cell metabolism of galactose in vitro is inhibited by ethanol, but this inhibition is not reversed by menthol or progesterone. Depression by ethanol of galactose oxidation in human liver in vitro is reversed by menthol, as has been observed in other animal species.