Growth of Neurotropic Viruses in Extraneural Tissues IV. Poliomyelitis Virus in Human Testicular Tissue In vitro.

Abstract

Summary The Lansing and Hof. strains of poliomyelitis virus multiplied extensively in tissue cultures of testes from men 57 to 93 years old, most of whom had carcinoma of the prostate gland. Lansing virus was carried through 8 successive tissue cultures and Hof. virus was carried through 7 cultures. Several less extensive series were completed with each virus. The amount of Hof. virus in these tissue cultures per milligram of tissue was approximately the same as was obtained in infected monkey spinal cords.