Mitochondria: A therapeutic target in neurodegeneration
- 1 January 2010
- journal article
- review article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Vol. 1802 (1), 212-220
- https://doi.org/10.1016/j.bbadis.2009.10.007
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (AG031852, AG026151)
This publication has 132 references indexed in Scilit:
- The effect of acetyl-L-carnitine and R-α-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's diseaseJournal of the Neurological Sciences, 2009
- Mitochondrial DNA damage is a hallmark of chemically induced and the R6/2 transgenic model of Huntington's diseaseDNA Repair, 2009
- Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteinsProceedings of the National Academy of Sciences, 2008
- Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's diseaseNature Medicine, 2008
- Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease BrainJournal of Biological Chemistry, 2008
- Selective defect of in vivo glycolysis in early Huntington's disease striatumProceedings of the National Academy of Sciences, 2007
- Free radicals and antioxidants in normal physiological functions and human diseaseThe International Journal of Biochemistry & Cell Biology, 2007
- Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and α-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's diseaseFree Radical Biology & Medicine, 2006
- Impaired platelet mitochondrial activity in Alzheimer’s disease and mild cognitive impairmentMitochondrion, 2006
- Radical medicine: treating ageing to cure diseaseNature Reviews Molecular Cell Biology, 2005