A COMPARISON OF THE RENAL REABSORPTIVE PROCESSES FOR SEVERAL AMINO ACIDS

Abstract

A comparison was made in the dog of renal tubular reabsorption of amino N at various arterial plasma levels of glycin, alanine, glutamic acid, arginine and the amino acids of hydrolyzed casein. The amts. of the various amino acids reabsorbed stand in decreasing order of glycin, alanine, glutamic acid and arginine, at all amts. filtered. The amt. of casein hydrolysate reabsorbed lies between glycin and alanine in the lower range of plasma conc. and between alanine and glutamic acid in the upper range. Glycin, alanine, glutamic acid and arginine are reabsorbed by a common renal mechanism. The rather considerable differences in their rates of reabsorption probably result from differences in their rates of combination with some cellular component common to the reabsorptive system for all.