Whole Body X-Irradiation of Obese Mice

Abstract

Mice made fat by gold thioglucose injn. and mice with hereditary adiposity had the same incidence of death following whole body X-irradiation as litter-mate controls of normal size. Survival time and wt. loss after radiation were the same in fat as in control mice, while in nonirradiated starved mice survival time and total wt. loss were about 3 times as great in the obese mice as in their controls. These results strongly suggest that starvation is not responsible for death in mice following radiation either in the range where survival time is 9 to 14 days (500 r) or 3.5 to 4 days (2000 r).