Catabolite repression in the gram‐positive bacteria: Generation of negative regulators of transcription

Abstract

Operons subject to catabolite repression (CR) in the gram‐positive bacteria appear to be transcriptionally regulated by negative acting catabolite repressors. Cis elements within the promoter regions of a few CR operons have been identified as the target sequences for these repressors. It has also been proposed that sequences internal to the transcriptional unit may represent targets for recognition of the operons as catabolite repressible. The precise mechanism(s) of regulation have yet to be worked out.