Topogenesis of peroxisomal proteins
- 1 May 1990
- Vol. 12 (5), 217-222
- https://doi.org/10.1002/bies.950120505
Abstract
Molecular and biochemical analysis of the biogenesis of peroxisomes has made rapid progress in recent years. Research on the mechanism of targeting of peroxisomal proteins has revealed that many, but not all, peroxisomal proteins have a conserved tripeptide motif in their carboxy‐terminal portions which is required for entry into peroxisomes; the topogenic signal mechanism thus differs in these instances from those employed in mitochondria and endoplasmic reticulum. Other factors involved in peroxisome biogenesis are also coming to light.Keywords
This publication has 32 references indexed in Scilit:
- Isolation and characterization of Chinese hamster ovary cell mutants defective in assembly of peroxisomes.The Journal of cell biology, 1990
- A 42K outer-membrane protein is a component of the yeast mitochondrial protein import siteNature, 1989
- Expression and transport of Candida tropicalis peroxisomal acyl-coenzyme A oxidase in the yeast Candida maltosa.Agricultural and Biological Chemistry, 1989
- Protein Translocation Across MembranesScience, 1988
- A family of closely related ATP‐binding subunits from prokaryotic and eukaryotic cellsBioEssays, 1988
- Identification of a receptor for protein import into chloroplasts and its localization to envelope contact zonesNature, 1988
- Identification of a peroxisomal targeting signal at the carboxy terminus of firefly luciferase.The Journal of cell biology, 1987
- Translocation of acyl-CoA oxidase into peroxisomes requires ATP hydrolysis but not a membrane potential.The Journal of cell biology, 1987
- Three-dimensional reconstruction of a peroxisomal reticulum in regenerating rat liver: evidence of interconnections between heterogeneous segments.The Journal of cell biology, 1987
- Proton ionophores prevent assembly of a peroxisomal proteinCell, 1987