Isotopic labeling of phosphatidylcholine in the choline moiety
- 1 January 1978
- Vol. 13 (1), 92-94
- https://doi.org/10.1007/bf02533373
Abstract
Two simple methods for the synthesis of phosphatidylcholine (lecithin) isotopically labeled in the methyl group of the choline moiety are described. Phosphatidylcholine is converted to phosphatidyl‐ethanolamine by enzymic transphosphatidylation, and this is methylated using either methyl iodide or diazomethane to give a product isotopically enriched in all three choline methyl groups.This publication has 11 references indexed in Scilit:
- Conformation and motion of the choline head group in bilayers of dipalmitoyl-3-sn-phosphatidylcholineBiochemistry, 1975
- Asymmetric exchange of vesicle phospholipids catalyzed by the phosphatidylcholine exchange protein. Measurement of inside-outside transitionsBiochemistry, 1975
- Catalytic properties of phospholipid exchange protein from bovine heartBiochimica et Biophysica Acta (BBA) - Biomembranes, 1975
- A study of mobility and order in model membranes using 2H NMR relaxation rates and quadrupole splittings of specifically deuterated lipidsBiochemical and Biophysical Research Communications, 1974
- Nuclear Magnetic Relaxation and the Biological MembranePublished by Springer Nature ,1974
- A Simple Chemical Method for Labelling Phosphatidylcholine and Sphingomyelin in the Choline MoietyHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1971
- Synthesis of lecithins by acylation of O-(sn-glycero-3-phosphoryl) choline with fatty acid anhydridesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1969
- [38] Phospholipase D from savoy cabbageMethods in Enzymology, 1969
- Transphosphatidylation by Phospholipase DJournal of Biological Chemistry, 1967
- CONTRIBUTION TO THE SYNTHESIS OF ORGANIC DEUTERIUM COMPOUNDS: I. DEUTEROPOLYMETHYLENECanadian Journal of Research, 1950