Multiple Osteomatosis, Fibromas, Lipomas and Fibrosarcomas of the Skin and Mesentery, Epidermoid Inclusion Cysts of the Skin, Leiomyomas and Multiple Intestinal Polyposis

Abstract

A WELL defined syndrome consisting of multiple osteomas of the facial bones, sebaceous or epidermoid cysts of the skin, multiple polyposis of the large bowel and desmoids or fibromas of the skin was found in one family by Gardner and his co-workers^{1 2 3} in 1953–54.In 1943, Fitzgerald⁴ described a woman with desmoids, bony exostoses, scoliosis, multiple cystic odontomas, torus palatinus and multiple polyps of the bowel.O'Brien and Wells,⁵ in 1955, described a family in which 6 members had benign fibrous-tissue tumors in association with multiple polyposis. The former included desmoids of the abdominal wall, mesenteric fibromas and osteomas of . . .