Blood, Plasma and "Globulin" Space of Guinea Pigs Determined with I131 Rabbit Globulin
- 1 October 1951
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 78 (1), 264-266
- https://doi.org/10.3181/00379727-78-19040
Abstract
The blood and plasma volumes of guinea pigs were determined by the dilution of intraven. I131_trace-iodinated rabbit globulin. The avg. 8 to 15 min. dilution blood volume was found to be 7.53 + 0.71 cc/100 g. body wt. and the avg. plasma volume was 3.94 + 0.37 cc/100 g. body wt. The labelled rabbit globulin was found to mix slowly over a period of 20 hrs. into a larger body fluid volume, "globulin" space, which was found to have a min. value of 7.58 cc/100 g. body wt.,. which includes the peripheral plasma volume and a number of undetermined compartments.Keywords
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