Convenient Preparation of Dissymmetrical Diesters of N-Boc Glutamic Acid
- 1 September 1990
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 20 (17), 2585-2588
- https://doi.org/10.1080/00397919008051465
Abstract
Potassium cyanide is an efficient catalyst for the alcoholysis of various N-Boc pyroglutamates. The sequence provides a convenient preparation of dissymmetrical α— and γ—glutamate diesters.Keywords
This publication has 5 references indexed in Scilit:
- Synthesis of (2S,4S)- and (2S,4R)-4-Substituted Glutamic Acid Analogues for Neuroexcitatory Activity StudiesHETEROCYCLES, 1990
- Amino acid synthesis using ()-pyroglutamic acid as a chiral starting materialTetrahedron, 1989
- Synthesis of nonproteinogenic amino acids part 2: preparation of a synthetic equivalent of the γ anion synthon for asymmetric amino acid synthesisTetrahedron, 1989
- Direct Chain Elongation of N-Carbamoylpyroglutamate. An Efficient Synthesis of (−)-Pyrrolidine-2,5-Dicarboxylic AcidChemistry Letters, 1987
- A mild two-step method for the hydrolysis of lactams and secondary amidesThe Journal of Organic Chemistry, 1983