Possible involvement of protein kinase C in the stimulation of amino acid transport by phorbol ester, platelet-derived growth factor and A23187 in Swiss 3T3 cells
- 1 September 1986
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 42 (9), 1038-1040
- https://doi.org/10.1007/bf01940722
Abstract
Summary Stimulation of amino acid transport induced by phorbol-12, 13-dibutyrate, platelet-derived growth factor or A23187 was not observed in cells lacking protein kinase C. On the other hand, stimulation of transport by epidermal growth factor or insulin was not affected. These results suggested that the stimulation of amino acid transport is mediated by at least two separate pathways.Keywords
This publication has 21 references indexed in Scilit:
- Phosphorylation of the glucose transporter in vitro and in vivo by protein kinase CNature, 1985
- Ionic responses rapidly elicited by activation of protein kinase C in quiescent Swiss 3T3 cells.Proceedings of the National Academy of Sciences, 1985
- Stimulation of hexose transport by human polymorphonuclear leukocytes: A possible role for protein kinase CBiochemical and Biophysical Research Communications, 1985
- Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase.Proceedings of the National Academy of Sciences, 1984
- Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cellsBiochemical and Biophysical Research Communications, 1984
- Homologous and heterologous mitogenic desensitization of Swiss 3T3 cells to phorbol esters and vasopressin: Role of receptor and postreceptor stepsJournal of Cellular Physiology, 1984
- Human platelet-derived growth factor stimulates amino acid transport and protein synthesis by human diploid fibroblasts in plasma-free media.Proceedings of the National Academy of Sciences, 1982
- Regulation of amino acid transport in chicken embryo fibroblasts by purified multiplication-stimulating activity (MSA)Journal of Cellular Physiology, 1980
- A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samplesAnalytical Biochemistry, 1978
- Putrescine transport is greatly increased in human fibroblasts initiated to proliferate.The Journal of cell biology, 1976