Local T cell subsets in mumps meningitis.
Open Access
- 1 November 1983
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 58 (11), 927-928
- https://doi.org/10.1136/adc.58.11.927
Abstract
In the acute phase of mumps meningitis, more than 85% of the cells in cerebrospinal fluid (CSF) were OKT 3 positive, while 76% of the peripheral mononuclear cells (PMN) were OKT 3 positive. The ratio of OKT 4:8 positive cells in CSF was significantly lower than that in PMN, showing that suppressor/cytotoxic T cells had selectively accumulated in CSF. In addition, 58% of CSF cells were immune associated (Ia) positive, probably activated T cells.Keywords
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