Total Gonadotropin Activity in the Urine of Prepubertal Children
- 1 August 1967
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 27 (8), 1123-1128
- https://doi.org/10.1210/jcem-27-8-1123
Abstract
Four hundred fifty-nine 24-hr urine specimens from 44 normal children between the ages of 4 and 10 have been screened for total gonadotropin activity by means of the mouse uterus assay. Gonadotropins were detected at the 10 mouse uterus unit level in 1/6 of the specimens. Seventy-five per cent of the children had at least one 24-hr urine sample which yielded a positive result. No definite conclusions about the endocrine status of a prepubertal patient can be drawn from single random determinations of total urinary gonadotropin. A scheme is proposed for evaluating the results obtained from multiple 24-hr collections.Keywords
This publication has 2 references indexed in Scilit:
- ÜBER DIE AUSSCHEIDUNG VON FREIEM UND GLUCURONSÄUREGEBUNDENEM TESTOSTERON IM KINDES- UND REIFUNGSALTERActa Endocrinologica, 1967
- A CLINICAL ROUTINE-METHOD FOR THE QUANTITATIVE DETERMINATION OF GONADOTROPHINS IN 24-HOUR URINE SAMPLES, II: NORMAL VALUES FOR MEN AND WOMEN AT ALL AGE GROUPS FROM PRE-PUBERTY TO SENESCENCEActa Endocrinologica, 1959