Abstract
A method is described for the preparation of the [S35]sulphate ester of p-hydroxyphenylpyruvic acid. The sulphate ester, like the parent phenol, exhibits keto-enol tautomerism and undergoes spontaneous conversion into p-hydroxybenzaldehyde [S35]sulphate at pH greater than 11. Spontaneous conversion of the ester into p-hydroxyphenylacetic acid [S35]sulphate occurs on paper chromatograms.