The Effects of Castration on Adrenal Testosterone Secretion in Men with Prostatic Carcinoma
- 1 December 1977
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 118 (6), 1019-1021
- https://doi.org/10.1016/s0022-5347(17)58283-x
Abstract
Selective adrenal vein catheterization was done on intact and castrated men with prostatic carcinoma. Adrenal to peripheral venous testosterone gradients were observed in all patients, indicating adrenal production of this hormone. No compensatory adrenal production of testosterone was noted during a 17 mo. period after orchiectomy. The human adrenal in castrates produces testosterone, which may explain why adrenal ablation can offer palliation in some patients with prostatic carcinoma.This publication has 19 references indexed in Scilit:
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