The kinetics of acid hydrolysis of dipeptides
- 1 January 1956
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 62 (1), 154-159
- https://doi.org/10.1042/bj0620154
Abstract
The velocity constants for the hydrolysis of a series of synthetic dipeptides in aqueous 2N-HCl at 99" were determined. Dipeptides containing C-terminal serine and aspartic acid were especially labile, whereas peptides containing leucine were particularly resistant to hydrolysis. Significance of these results in relation to the more general problems of acid hydrolysis of proteins was discussed.Keywords
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