Transient, Severe Periventricular Hypodensity After Leukemic Prophylaxis with Cranial Irradiation and Intrathecal Methotrexate

Abstract
Serial computed tomography (CT) demonstrated complete resolution of severe periventricular hypodensity occurring in a child after receiving prophylaxis for acute lymphocytic leukemia. Early changes of subacute necrotizing leukoencephalopathy were reversible and CT was capable of detecting these early changes.