EFFECT OF PURIFIED FRACTIONS OF TUBERCULIN ON LEUKOCYTES FROM NORMAL AND TUBERCULOUS ANIMALS IN TISSUE CULTURES
- 1 January 1952
- journal article
- research article
- Published by Elsevier
- Vol. 65 (3), 250-271
- https://doi.org/10.1164/art.1952.65.3.250
Abstract
Old Tuberculin and standard purified protein derivative were found to produce a specific inhibition to migration and to cause injury to tuberculous leukocytes. Injury to the cells also occurred, as seen by granulation, agglutination, vacuolization, and disintegration. Tuberculin nucleic acid, commercial thymus nucleic acid, and a highly purified thymus nucleic acid produced no significant inhibitory effect on tuberculous leukocytes.Keywords
This publication has 9 references indexed in Scilit:
- Antigenic Differences in Two Tuberculin Protein FractionsThe Journal of Infectious Diseases, 1951
- THE NATURE OF THE TUBERCULIN REACTION - FAILURE TO DEMONSTRATE INVITRO CYTOTOXICITY OF TUBERCULIN FOR THE CELLS OF SENSITIZED ANIMALSPublished by Elsevier ,1951
- Comparative Immunizing Capacity of BCG and the Proteins and Polysaccharides in Tubercle Bacillus Culture FiltratesThe Journal of Immunology, 1950
- Comparison of the Filtrate Fractions and of Certain Bacillary Extracts of the H 37, H 37 RV and H 37 RA Strains of Tubercle Bacilli1Journal of the American Chemical Society, 1950
- STUDIES ON THE VIRULENCE OF TUBERCLE BACILLIThe Journal of Experimental Medicine, 1950
- THE ISOLATION OF 3 DIFFERENT PROTEINS AND 2 POLYSACCHARIDES FROM TUBERCULIN BY ALCOHOL FRACTIONATION - THEIR CHEMICAL AND BIOLOGICAL PROPERTIESPublished by Elsevier ,1949
- An antigenic polysaccharide, “polysaccharide II”, isolated from tuberculinBiochimica et Biophysica Acta, 1949
- Development of Tuberculous Infection. In vivo Observations in the Rabbit Ear Chamber.Experimental Biology and Medicine, 1948
- THE EFFECT OF PURIFIED FRACTIONS OF TUBERCULIN ON TUBERCULIN-SENSITIVE TISSUE - QUANTITATIVE STUDIES ON TISSUE CULTURESPublished by Elsevier ,1946