The common fragile site in band q27 of the human X chromosome is not coincident with the fragile X
- 28 June 2008
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 37 (3), 167-172
- https://doi.org/10.1111/j.1399-0004.1990.tb03498.x
Abstract
The common fragile site on the end of the long arm of the human X chromosome has been shown to be at a different location from the rare fragile site which produces the fragile X syndrome of intellectual handicap. The different locations can be clearly seen in chromosomes at about the 550 band level of resolution. This finding should help resolve difficulties in fragile X cytogenetics where expression of the common fragile site can lead to false positive diagnoses.Keywords
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