THE PHYSIOLOGICAL ACTIVITIES OF THE STEREOISOMERS OF THYROXINE
- 1 May 1949
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 44 (5), 445-448
- https://doi.org/10.1210/endo-44-5-445
Abstract
The thyroxine requirement of the rat was found to be 2.3 [mu]g./100g./day of DL-thyroxine, 1.5 [mu]g. of L-thyroxine and 5 [mu]g. of D-thyroxine. D-thyroxine has biological activity in the rat equal to 0.3 times that of L-thyroxine. This result has been obtained by direct comparison of the D- and L-isomers and also by calculation from the L:DL ratio.Keywords
This publication has 5 references indexed in Scilit:
- THE QUANTITATIVE DETERMINATION OF THYROXINE IN IODINATED CASEIN HAVING THYROIDAL ACTIVITYJournal of Biological Chemistry, 1945
- THE RELATIVE THYROIDAL POTENCY OF 1- AND d,1-THYROXINE1Endocrinology, 1945
- THE CALORIGENIC ACTION OF D- AND L-THYROXINJournal of Clinical Investigation, 1935
- Quantitative observations on thyroxine and allied substancesThe Journal of Physiology, 1930
- Resolution of dl-thyroxineBiochemical Journal, 1928