HEMOGLOBIN REGENERATION AS INFLUENCED BY DIET AND OTHER FACTORS

Abstract

Experiments usually have a past history or a genealogical sequence, and it may be appropriate at this time to review the genealogy of the liver diet experiments in anemia due to loss of blood in dogs. With Dr. Sperry in 1908 we¹ took up a study of the liver injury produced by chloroform anesthesia, giving particular attention to the regeneration of the liver cells to repair this injury. Icterus invariably is present in dogs with liver injury of this character, and this condition was studied further. With Dr. King we² studied obstructive jaundice and found that the bile pigments were absorbed from the liver into the blood capillaries direct rather than by way of the lymphatics. With Dr. Hooper in 1912 we³ began a systematic study of bile pigment production in the body as influenced by the Eck fistula and finally⁴ were able to show that