Regional Cochlear Blood Flow Studied by Observation of Microspheres in Serial Sections

Abstract
Using the microsphere method combined with light microscopic observation of serially sectioned plastic-embedded cochleas, the distribution of microspheres trapped within the cochlea can be observed and the regional blood flow can be determined. In the guinea pig, the blood flow is greatest in the lateral wall, high in the modiolus, and low under the organ of Corti.