Serum Myoglobin Levels Predicted from Serum Enzyme Values

Abstract

MYOGLOBINURIA is generally considered uncommon, although it has been reported in a wide variety of clinical conditions.¹ The potential for acute tubular necrosis and renal failure associated with myoglobinuria is widely recognized. However, little information is available associating myoglobin levels with pathologic effects on the kidney. The scarcity of such information is related, in part, to the fact that quantitative myoglobin assays have been technically difficult to perform and not well suited for clinical use.In several case reports in which myoglobinuria and myoglobinemia have been documented, elevated serum enzyme values have been offered as confirmatory evidence of muscle injury. . . .