Anti-autolysis of Trypsin by Modification of Autolytic Site Arg117
- 18 September 1998
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 250 (2), 235-239
- https://doi.org/10.1006/bbrc.1998.9295
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Two Mutations in Rat Trypsin Confer Resistance against AutolysisBiochemical and Biophysical Research Communications, 1998
- A rapid and effective procedure for screening protease mutantsProtein Engineering, Design and Selection, 1996
- A genetic selection elucidates structural determinants of arginine versus lysine specificity in trypsinGene, 1993
- Relocating a Negative Charge in the Binding Pocket of TrypsinJournal of Molecular Biology, 1993
- Structure of an engineered, metal-actuated switch in trypsinBiochemistry, 1993
- Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214Biochemistry, 1992
- An investigation into the minimum requirements for peptide hydrolysis by mutation of the catalytic triad of trypsinJournal of the American Chemical Society, 1992
- Introduction of a cysteine protease active site into trypsinBiochemistry, 1989
- Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsinBiochemistry, 1987
- Redesigning Trypsin: Alteration of Substrate SpecificityScience, 1985