Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer
Top Cited Papers
- 1 July 2008
- journal article
- Published by Elsevier in Journal of Controlled Release
- Vol. 129 (2), 107-116
- https://doi.org/10.1016/j.jconrel.2008.03.008
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptideBiochemical and Biophysical Research Communications, 2007
- INTRAVENOUSLY ADMINISTERED SHORT INTERFERING RNA ACCUMULATES IN THE KIDNEY AND SELECTIVELY SUPPRESSES GENE FUNCTION IN RENAL PROXIMAL TUBULESDrug Metabolism and Disposition, 2006
- Angiogenesis inhibitors in the treatment of cancerExpert Opinion on Pharmacotherapy, 2005
- Lactosylated Poly(ethylene glycol)-siRNA Conjugate through Acid-Labile β-Thiopropionate Linkage to Construct pH-Sensitive Polyion Complex Micelles Achieving Enhanced Gene Silencing in Hepatoma CellsJournal of the American Chemical Society, 2005
- Interferon alpha 2a downregulates VEGF expression through PI3 kinase and MAP kinase signaling pathwaysZeitschrift für Krebsforschung und Klinische Onkologie, 2004
- siRNAs: applications in functional genomics and potential as therapeuticsNature Reviews Drug Discovery, 2004
- Biodistribution of phosphodiester and phosphorothioate siRNABioorganic & Medicinal Chemistry Letters, 2004
- Killing the messenger: short RNAs that silence gene expressionNature Reviews Molecular Cell Biology, 2003
- RNA interferenceNature, 2002
- Polyion complex micelles as vectors in gene therapy – pharmacokinetics and in vivo gene transferGene Therapy, 2002