Styrene and styrene oxide induce SCEs and are metabolised in human lymphocyte cultures
- 1 January 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 1 (4), 357-361
- https://doi.org/10.1093/carcin/1.4.357
Abstract
Both styrene and its presumed active metabolite styrene oxide show dose response as potent inducers of sister chromatid exchanges (SCEs) in human lymphocyte cultures. The SCE inducing and clastogenic capacity of styrene in lymphocytes in vitro can be explained by gas chromatographically measurable increase of styrene oxide in styrene treated cultures.This publication has 12 references indexed in Scilit:
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