Enhancement by Lysozyme of the Sensitivity of Treponema Pallidum Immobilization Tests
Open Access
- 1 March 1963
- journal article
- research article
- Published by BMJ in Sexually Transmitted Infections
- Vol. 39 (1), 37-40
- https://doi.org/10.1136/sti.39.1.37
Abstract
The incorporation of 0.0075% lysozyme in treponemal survival medium effects a 3- to 4-fold increase in the sensitivity of tests for specific T. pallidum immobilizing (TPI) antibody. This increase, superimposed on that achieved by incubating for 40 hours instead of the usual 18 hours, resulted respectively in 7-to 8-fold and 15- to 16-fold mean increases in the titers of syphilitic human and rabbit sera. Practical applications in the sero-diagnosis of syphilis are demonstrated.Keywords
This publication has 8 references indexed in Scilit:
- SENSIBILISATION, PAR LE LYSOZYME, DU TEST DIMMOBILISATION DES TREPONEMES1962
- Diagnostic Utility of the 40-Hour TPI TestAmerican Journal of Clinical Pathology, 1961
- INFLUENCE OF LYSOZYME UPON THE TREPONEME IMMOBILIZATION REACTION1American Journal of Epidemiology, 1961
- Lyophilized Survival Medium for the T. Pallidum Immobilization TestSexually Transmitted Infections, 1958
- Procedure for increasing the sensitivity of tests for specific treponemal antibody.1958
- Studies on Treponemal Immobilizing Antibodies in SyphilisThe Journal of Immunology, 1951
- STUDIES ON TREPONEMAL IMMOBILIZING ANTIBODIES IN SYPHILIS .1. TECHNIQUES OF MEASUREMENT AND FACTORS INFLUENCING IMMOBILIZATION1951
- Studies on treponemal immobilizing antibodies in syphilis; incidence in serum and cerebrospinal fluid in human beings and absence in biologic false positive reactors.1950